Construct a Blog post, not to exceed 1,500–2,000 words, written for a PMHNP provider audience to post in the Discussion area. Although you are not required to respond to colleagues, collegial discussion is welcome. Also, it will be important for you to read your peers’ Blog posts in order to learn about all of the medications on the assigned list. You will be assigned from the following list: Opioid Use Disorder Vivitrol Suboxone Methadone Lofexidine

Construct a Blog post, not to exceed 1,500–2,000 words, written for a PMHNP provider audience to post in the Discussion area. Although you are not required to respond to colleagues, collegial discussion is welcome. Also, it will be important for you to read your peers’ Blog posts in order to learn about all of the medications on the assigned list. You will be assigned from the following list: Opioid Use Disorder Vivitrol Suboxone Methadone Lofexidine

 
In this Blog, you will have the opportunity to teach your peers about a specific substance use and/or addiction/impulse control disorder. A Blog is a conversational, informal written piece on a topic. Your faculty will assign you a particular illness and the approved treatment for the illness to create a presentation to share with your peers. Construct a Blog post, not to exceed 1,500–2,000 words, written for a PMHNP provider audience to post in the Discussion area. Although you are not required to respond to colleagues, collegial discussion is welcome. Also, it will be important for you to read your peers’ Blog posts in order to learn about all of the medications on the assigned list. You will be assigned from the following list: Opioid Use Disorder Vivitrol Suboxone Methadone Lofexidine Alcohol Use Disorder Acamprosate Naltrexone Disulfiram Phenobarbital (seizure control due to alcohol withdrawal) Chlordiazepoxide Cannabis Use Disorder Nefazodone* Fluoxetine* Gabapentin* Buspirone* Stimulant Use Disorder (cocaine, methamphetamine) Antipsychotic Medications* Combination Injectable Naltrexone* Bupropion* Gabapentin* Tobacco Use Disorder Nicotine replacement patch Nicotine replacement gum Nicotine replacement inhaler Zyban Sedative/Hypnotic Anxiolytic Use Disorder Gabapentin* Buspirone* Flumazenil* Trazodone* Binge Eating Disorder (BED) Lisdexamphetamine *Indicates not FDA approved.
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Opioid Use Disorder and Its Treatment

Hello fellow PMHNP providers! Today, I'd like to discuss a prevalent issue in our field: Opioid Use Disorder (OUD) and its approved treatments. OUD is a chronic, relapsing illness, associated with significant morbidity and mortality. But fortunately, effective treatments are available that can help people with OUD to live healthy and productive lives.

Approved Treatments for OUD

Here are some of the FDA-approved medications for the treatment of OUD:
  1. Vivitrol (Naltrexone): An opioid antagonist that blocks the effects of opioids. It is non-addictive and does not lead to physical dependence. It is administered once a month by injection.
  2. Suboxone (Buprenorphine and Naloxone): A combination of buprenorphine (a partial opioid agonist) and naloxone (an opioid antagonist). It is used to prevent withdrawal symptoms when someone stops taking opioid drugs by producing similar effects to these drugs.
  3. Methadone: A long-acting opioid agonist, Methadone is administered under a physician's supervision. It helps reduce cravings and withdrawal symptoms in people with OUD.
  4. Lofexidine: A non-opioid medication that can help reduce opioid withdrawal symptoms.
Medication Mechanism of Action Administration
Vivitrol Opioid antagonist Monthly injection
Suboxone Partial opioid agonist/antagonist Oral
Methadone Opioid agonist Oral under supervision
Lofexidine Non-opioid Oral

Off-label Treatments

While not FDA-approved specifically for OUD, some medications have been used off-label for this purpose. These include:
  • Gabapentin: Originally used for seizure disorders, it has been found to help with opioid withdrawal symptoms.
  • Buspirone: An anti-anxiety medication, it may help with symptoms of opioid withdrawal.
Note: Off-label use should be considered carefully, taking into account the individual patient's condition and potential risks and benefits.

Conclusion

Opioid Use Disorder is a significant public health issue, but effective treatments are available. As PMHNP providers, we play a crucial role in helping our patients navigate their treatment options and supporting them through their recovery journey. Remember, every patient is unique, and what works for one may not work for another. Therefore, it's essential to individualize treatment plans and continually reassess and adjust as necessary. I hope this blog post has been informative and helpful. I look forward to reading your posts on other substance use disorders and their treatments. Let's continue to learn from each other and strive to provide the best care for our patients.

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