1. Kathryn A 19-year-old co-ed presents with increasing diarrhea and constipation over the last two weeks. She has a history of celiac disease. Celiac Disease and Diabetes Insipidus Gluten-related diseases such as celiac disease and gluten ataxia are rare conditions, affecting roughly less than 1% of t

eliac Disease and Diabetes Insipidus

Hello Kathryn

Thanks for discussing the patient’s case with a history of celiac disease. The discussion is good, and the case presented enhances understanding of celiac disease. Other than understanding that a gluten-free lifestyle is essential for managing celiac disease, it explains the physiology of the condition. I would, however, like to highlight that the case presented was a reoccurring occurrence of celiac disease; therefore, it would be essential to consider the possible triggers that could have made the disease active again. For instance, it’s known that severe emotional stress, surgery, pregnancy, infection, or childbirth can cause celiac disease even after a patient has successfully managed the condition before.

Recommending supplements that reduce gluten senility or intolerance, like vitamin D, magnesium, and calcium, should reduce the severity of celiac symptoms (Naik et al., 2018). To minimize the occurrence, I would also recommend that the patient take digestive enzymes before meals to help digestion, facilitating healing and reversing the celiac symptoms.

References

Naik, R. D., Seidner, D. L., & Adams, D. W. (2018). Nutritional consideration in celiac disease and non-celiac gluten sensitivity. Gastroenterology Clinics, 47(1), 139-

 Hello Amber

Great response!! I agree with you that the sodium levels for the case patient diagnosed with diabetes Ininsipidus should be high; given her case, she presents symptoms of urinary tract infection, but no disease was found following the diagnosis and treatment for management. Sodium levels are high because of increased urine frequency, leading to water loss in the body, resulting in polydipsia. The rationale for elevated osmolality is embedded in the increased frequency of water loss during urine excretion, resulting in a higher concentration of particles in the serum since the blood contains insufficient water.

The comparison is simple; while central diabetes Ininsipiduss is associated with insufficient ADH, nephrogenic Diabetes Insipidus is related to the failure of kidneys to concentrate the urine caused by impaired renal tubule (Bichet, 2020). For nephrogenic Diabetes Insipidus, the DH is available and sufficient, but the failure of the kidneys leads to the excretion of vast amounts of dilute urine. dDAVP works by increasing the concretion of VWF, FVIII, and