Describe the changes seen in the brain structure in patients with PTSD

. Changes in the brain structure in patients with PTSD emanates from severe emotional trauma that causes lasting alterations in the ventromedial prefrontal cortex region of the brain. Prefrontal cortex is responsible for the regulation of responses triggered by amygdale. PTSD patients show a marked decrease in the volume of the ventromedial prefrontal cortex and the functional ability of this region. For instance, the patient in this scenario grudgingly admits to having experienced several traumatic events during his second tour of duty, indicating alterations in the ventromedial prefrontal cortex region of the brain. Question 2 of 2: Briefly discuss the role glucocorticoids may have on the development of PTSD Glucocorticoids play an important role in the development of PTSD. Notably, moderate secretion of glucocorticoids enhances a patients’ coping mechanism by helping them to process information is a way that reduces the retrieval of fear-evoking memories. However, when there is inadequate production of glucocorticoids such as cortisol, which is a stress hormone, the individuals may have problems to emotionally adapt following a traumatic event as seen in the patient in this scenario.