ENGL 148 Research Paper Overall Effectiveness of Overdose Reversing Drugs

ENGL 148 Research Paper Overall Effectiveness of Overdose Reversing Drugs

 

The effectiveness of overdose-reversing drugs

An overdose occurs when a person ingests a toxic amount of drugs or medicine, which can lead to a medical emergency. In some cases, overdoses can be fatal. Medical practitioners may contribute to drug overdoses through dosing errors, psychological factors, and pharmacological interactions. In the United States, the opioid crisis has resulted in a public health crisis, with a growing number of overdose deaths. In 2017, for instance, 47,600 people died from opioid overdoses, making accidental overdose more deadly than traffic accidents or gun deaths (Warner & Hedegaard, 2018).

Today, drug overdose deaths have reached an all-time high, devastating communities and families, with over 104,000 Americans dying of drug overdoses (Warner & Hedegaard, 2018). Health stakeholders and facilities have responded to the crisis by introducing overdose-reversing drugs and antidotes, such as Acetaminophen, Flumazenil, Naloxone, Diazepam, and Midazolam. Naloxone is the most effective overdose reversal drug, and it can reverse most overdoses, making it applicable to most patients. Therefore, it is crucial to recognize that the increasing availability and access to opioid drugs requires the use of overdose-reversing drugs to prevent overdose fatalities.

ENGL 148 Research Paper Overall Effectiveness of Overdose Reversing Drugs

The prescribing of opioids by medical practitioners, including nurses, has increased over time. The introduction of OxyContin in the 1990s to providers and pain clinics facilitated the adoption of overdose reversal drugs. This helped to provide a safer, healthier alternative for people who overdose on drugs prescribed by clinics and health facilities. However, the opioid crisis narrative by the CDC raised concerns about the use of overdose reversal drugs due to the rising number of overdose deaths resulting from prescribed opioids. The availability and production of these drugs have contributed to the increase in overdoses, resulting from addiction to pain relievers. Prolonged use, non-medical use, and misuse of opioids in treating pain have led to health problems and challenges such as dependence. To mitigate these risks, overdose-reversal drugs such as naloxone should be allowed as an antidote to opioids, reversing the effects of the opioid in time.

To prevent opioid addiction, various programs and interventions have been implemented to reduce access and prescription in many health facilities and providers. Prescription Drug Monitoring Programs (PDMPs), for instance, aim to track painkiller prescriptions and make data available in real-time. PDMPs are meant to limit the number of overdose deaths by regulating the dose and prescription. However, they have not effectively reduced the number of overdose deaths, which have mostly been linked to illicit opioids such as fentanyl and heroin. Although PDMPs monitor prescriptions, they do not curb access and contact with illegal drugs. To address this issue, governments, healthcare stakeholders, and pharmaceutical companies need to consider the importance of overdose-reversal drugs, given that most overdose cases result from the use of illicit drugs. Flumazenil, Naloxone, Diazepam, and Midazolam are some drugs that can help reverse opioid overdose as a preventive and rehabilitative measure. Using these drugs effectively saves many people from life-threatening conditions such as bleeding, respiratory depression, and bradycardia. Naloxone, in particular, is an effective overdose-reversal drug that does not affect someone with no opioids in their system. Statistical modeling indicates that if pharmaceutical companies and health stakeholders distribute high rates of naloxone among emergency personnel and laypeople, it could prevent 21% of opioid overdose deaths. The drug works by restoring the regular breathing system by blocking any effects caused by opioids, making it an effective opioid antagonist.

With the rise of illicit opioids and prescription drugs, overdose-reversing medications have become crucial in reducing and preventing overdose fatalities. The lack of consumer information and quality control in the underground markets where most people acquire illegal drugs poses a significant challenge. The ethical concerns surrounding the effectiveness of these drugs require moral decision-making since addiction and black markets are major issues.

ENGL 148 Research Paper Overall Effectiveness of Overdose Reversing Drugs

Opioid use has devastating effects on public health and safety, resulting in overwhelming psychological and physiological impacts and dependency levels. As a result, society tends to view individuals struggling with opioid addiction as fraught with misperceptions, emotions, and biases. Substance treatment poses dilemmas related to individual values, judgments, and

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