Q4. Please discuss the side effect profile of each medication you listed.

Hydrochlorothiazide, despite being frequently prescribed, exhibits limited

conventional adverse effects, including electrolyte imbalances, hyperglycemia,

hyperlipidemia, and hyperuricemia (Kumar et al., 2022). Nevertheless, the

authorities considered it to be the primary recommendation for the management of

hypertension. The administration of HCZT has the potential to result in the

development of hypokalemia, hyponatremia, hypercalcemia, and

hypomagnesemia. Additionally, in individuals with impaired renal function, HCZT

may lead to the occurrence of azotemia.

Amlodipine is associated with notable adverse effects, such as peripheral

edema, heart failure, pulmonary edema, flushing, dizziness, headache, drowsiness,

skin rash, nausea, abdominal pain, and constipation (Bulsara & Cassagnol, 2023)