The Pathophysiology of the Alterations in Hepatic Disease

Hepatic disease, also known as liver disease, is a broad term that refers to any condition that affects the function and structure of the liver. The liver is a vital organ that performs numerous bodily functions, including detoxification, metabolism, and synthesis of essential proteins. The hepatic disease can result in alterations in liver function, leading to a wide range of symptoms and complications. The pathophysiology of the hepatic disease involves a complex interplay of genetic, environmental, and lifestyle factors that can damage the liver and disrupt its normal function (Violina et al. 3). Various factors, including viral infections, alcohol abuse, drug toxicity, autoimmune disorders, and metabolic disorders, can cause hepatic disease. These factors can lead to cellular damage, inflammation, and scarring of the liver tissue. In the early stages of hepatic disease, the liver may usually compensate for the damage and function (Paolo et al. 416). However, as the disease progresses, the liver becomes overwhelmed and can no longer perform everyday functions. This can lead to a buildup of toxins and waste products in the body, which can cause various symptoms and complications, including fatigue, jaundice, ascites, hepatic encephalopathy, and liver failure. The pathophysiology of hepatic disease also involves changes in the structure and function of liver cells (Zeljka et al. 797). In response to injury or inflammation, liver cells may undergo a process called fibrosis, in which scar tissue replaces healthy liver tissue. This can lead to a loss of liver function and further exacerbate the disease process. Hepatic disease is a complex and multifactorial condition that can alter liver function and structure. Understanding the pathophysiology of hepatic disease is essential for developing effective treatments and preventing complications.