What are panicogens and how do they contribute to the development of panic attack symptoms?

Panicogens are substances that cause panic or anxiety. They include sever stress, Yohimbine, CCK tetrapeptide (CCK-4), caffeine, m-chlorophenylpiperazine, and benzodiazepine partial inverse agonist FG 7142. These agents cause panic attack by increasing anxiety, nervousness, fear, nausea, palpitations, restlessness, and tremors. For instance, the patient in this scenario had chief complaint of palpitations, rapid heart rate, sweating, and tremors, which re all triggered by the panicogenic agents.