What is the advantage of combining levodopa with carbidopa? What is the benefit of anticholinergic drugs in the management of Parkinson disease?

The anticholinergic drugs help decrease signs and symptoms, thereby allowing the patients to hopefully provide self-care and maintain a reasonable quality of life. Anticholinergics provide benefits such as reduced tremor and rigidity. Sinemet (levodopacarbidopa) is both a immediate release and a controlled release drug that help improve motor function[Ign17]. The benefits of the combination of drugs help prevent a wearing off phenomenon which may impact dyskinesias with periods of good mobility then poor mobility.